WebStatins — erythromycin is an inhibitor of liver isoenzyme cytochrome P450 CYP3A4, which is particularly involved in the metabolism of simvastatin and atorvastatin. The risk of myopathy and/or rhabdomyolysis is increased with higher plasma concentrations of statins. For simvastatin — do not prescribe erythromycin to a person taking simvastatin. WebMar 9, 2024 · Pharmacodynamics. Clarithromycin is a macrolide antibiotic whose spectrum of activity includes many gram-positive (Staphylococcus aureus, S. pneumoniae, and S. pyogenes) and gram-negative aerobic bacteria (Haemophilus influenzae, H. parainfluenzae, and Moraxella catarrhalis), many anaerobic bacteria, some …
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WebThis may seem odd, but certain medications can interact with foods or beverages. For example, grapefruit juice can lower the levels of enzymes in your liver responsible for breaking down medications. Blood levels of an interacting drug may rise, leading to toxicity. This interaction can occur with the commonly used statins to lower cholesterol ... Web8 years to 17 years: 250–500 mg four times a day or 500-1000 mg twice a day. In children with severe renal impairment, the dose of erythromycin should be reduced. In adults, prescribe 250–500 mg four times a day. In adults with severe renal impairment, prescribe a maximum daily dose of 1.5 g of erythromycin. [ ABPI, 2024b; BNF 75, 2024 ... togher cork
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WebDec 11, 2014 · Drug interactions associated with increased risk of myopathy/rhabdomyolysis. Interacting agents Prescribing recommendations; Itraconazole Ketoconazole Posaconazole Erythromycin ... BNF section 2. ... WebThese classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate WebJan 3, 2024 · severe stomach pain; or. diarrhea that is watery or bloody (even if it occurs months after your last dose). Common amoxicillin side effects may include: nausea, vomiting, diarrhea; or. rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. peoples bank and trust rockford ohio