Flotillin family protein
WebApr 13, 2024 · Patellins, a protein family that has PI-binding activity, have been identified in plant-derived EVs, providing a basis for this hypothesis that requires future investigation. FCW = fungal cell wall, FM = fungal membrane, FMT = fungal memtub, FLOT/REM = flotillin/remorin, LE = late endosome, PCW = plant cell wall, PATL = patellin, PS = … WebAn important cell membrane protein is found to have a role in regulating ion transport in plant cells, which could help plants be more salt-tolerant. ... Flotillin proteins in the membranes of ...
Flotillin family protein
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WebCadherin-1 or Epithelial cadherin (E-cadherin), (not to be confused with the APC/C activator protein CDH1) is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers.CDH1 has also been designated as CD324 (cluster of differentiation 324). It is a tumor suppressor gene. WebTwo scaffold proteins, FLOTILLIN 4 (FLOT4) and the remorin protein SYMREM1, facilitate the formation of membrane nanodomains, reducing the mobility of the NF receptors, and this appears vital for appropriate rhizobial infection . While the symbiosis signalling pathway is important for infection, there is little evidence that this transduction ...
WebJun 26, 2013 · Background The flotillin family member flotillin-1 (FLOT1) encodes a caveolae-associated, integral membrane protein that belongs to lipid raft family and involves in vesicular trafficking and signal transduction. However, the role of FLOT1 in development and progression of cancer remains largely unknown. The present study … WebOct 25, 2011 · There are two homologous members in flotillin proteins family, flotillin-1 and flotillin-2. ... Hazarika et al. found that both flotillin-2 protein and mRNA were increased in tumorigenic and metastatic melanoma cell lines in vitro. SB2 melanoma cells altered to highly tumorigenic and metastatic in nude mice after transfection of flotillin-2.
WebFlotillin 2 is a direct transcriptional target of the p53 family member genes in human cancer cells. The interaction of flotillin-2 with amyloid precursor protein (APP) promotes the clustering of APP at the cell surface. Coassembly of flotillin1 and flotillin2 into microdomains induces membrane curvature, the formation of plasma-membrane ... WebSep 10, 2014 · The flotillin protein family consists of flotillin-1 and 2 (also called reggies) which homo- and hetero-oligomerize [2, 37]. Despite some other functions [ 4 , 32 ], flotillins have been linked to endocytosis and vesicular trafficking but also to signaling [ 6 , 8 , 14 , 15 , 24 , 33 , 36 , 38 ].
WebMar 21, 2024 · Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade; ... ATP-binding cassette, sub-family A (ABC1), member 1 forms a complex with syntaxin 13 and flotillin-1, residing at the plasma membrane and in phagosomes;
WebOct 28, 2024 · Membrane surveillance and repair is of utmost importance to maintain cellular integrity and allow cellular life. Several systems detect cell envelope stress caused by antimicrobial compounds and abiotic stresses such as solvents, pH-changes and temperature in bacteria. Proteins containing an Stomatin, Prohibitin, Flotillin, and HflK/C … city fun centerWebThus, flotillin-1 represents a new integral membrane protein marker for the slightly larger caveolae-related domains (50–200 nm) that are observed in cell types that fail to express caveolin-1. As a consequence of these findings, we propose the term “cavatellins” be used (instead of flotillins) to describe this gene family. did a crossword in a waiting roomWebFLOT1. Flotillin-1 is a protein that in humans is encoded by the FLOT1 gene. [5] Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal … did a cow really start the chicago fireWebOct 1, 2005 · The flotillin family is composed of two highly homologous proteins, flotillin 1 and flotillin 2, characterized by the presence of a prohibitin homology (PHB) domain, which is responsible for ... did a cow start the chicago fireWebanalysis of the cDNA for this protein has provided new avenues by which to explore the structure and function of caveolae organelles. Interestingly, flotillin is a close homologue … didact freeeWebSep 18, 2012 · The family of flotillin proteins consists of two homologous members, flotillin-1 and flotillin-2, also termed “reggies”, with flotillin-1 being identical to reggie-2 and flotillin-2 to reggie-1 , . Flotillins are … did a cow start the great chicago fireWebThe flotillin family is composed of two highly homologous proteins, flotillin-1 and flotillin-2 that share ~50% amino acid sequence similarity. ... Human Flotillin-1 recombinant … did a coyote get my cat