Mitoferrin regulation
WebMitoferrin 1 and mitoferrin 2 are homologous members of the mitochondrial solute carrier family. Mitoferrin 1 is required for mitochondrial iron delivery in developing … Web2 dec. 2016 · Intron retention (IR) regulates hundreds of erythroid genes in a differentiation stage-specific manner during terminal erythropoiesis. Regulated genes include highly …
Mitoferrin regulation
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WebIron Regulatory Protein 1 / metabolism* Liver Neoplasms* / genetics Phosphopyruvate Hydratase / genetics RNA, Messenger / genetics Tumor Suppressor Proteins / metabolism Biomarkers, Tumor DNA-Binding Proteins RNA, Messenger Tumor Suppressor Proteins Iron ENO1 protein, human Phosphopyruvate Hydratase ACO1 protein, human Iron … Webwere significantly reduced by green tea supplementation in w1118 and mitoferrin mutants but not transferrin mutant flies. Our results demonstrate that green tea may act to increase the lifespan of Drosophila in part by the regulation of mitoferrin and reduction of mitochondrial iron. Keywords green tea; iron; lifespan; fertility; mitoferrin ...
Web(2009) Paradkar et al. Molecular and Cellular Biology. Mitoferrin 1 and mitoferrin 2 are homologous members of the mitochondrial solute carrier family. Mitoferrin 1 is required … Web1 dec. 2001 · Function. Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid …
WebGDF15, hepcidin and mitoferrin-1 (mfrn-1) are proteins involved in systemic iron regulation. There are no studies in the literature demonstrating the serum mfrn-1 levels … Web20 dec. 2024 · Abstract Mitochondrial iron is indispensable for heme biosynthesis and iron–sulfur cluster assembly. Several mitochondrial transmembrane proteins have …
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Web11 apr. 2024 · Chen, W. et al. Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proc. Natl Acad. Sci. USA 106 , 16263–16268 (2009). fricks and bohan warner robinsWeb3 okt. 2016 · Total body and mitochondrial iron levels were significantly reduced by green tea supplementation in w 1118 and mitoferrin mutants but not transferrin mutant flies. Our results demonstrate that green tea may act to increase the lifespan of Drosophila in part by the regulation of mitoferrin and reduction of mitochondrial iron. frick santo angeloWebMitoferrin-1 has been implicated in diseases associated with defective iron homeostasis, resulting in iron or porphyrin imbalances. Abnormal Mfrn1 expression, … father son polo shirtsWeb2 nov. 2024 · miRNA regulation of mitoferrin-1 has been documented as well. RNA sequencing revealed the downregulation of SLC25A37 mRNA and protein expression, as … father son powershellWeb11 feb. 2024 · Transcriptional regulation may also exert a regulatory control of iron homeostasis. Although metal transcription factor (MTF)/metal regulatory element (MRE) system is not directly involved in iron regulation, Fer1HCH and Fer2LCH can be transcriptionally induced by MTF-1 under zinc or copper treatment [ 71 ], likely to store … father son poems relationshipWeb2 mrt. 2016 · In this study, we provide evidence, for the first time, that a mitoferrin is regulated by a miRNA. Specifically, we show that miR-8-3p regulates mitoferrin ( bmfrn … father son poses photographyWeb26 sep. 2014 · Thus, mitoferrin-2 may participate in As 2 O 3 treatment. Additionally, previous researches have reported that up-regulated expression of mitoferrin in yeast … father son pow wow